The exhibition program at the Nasher Sculpture Center encompasses and expands upon the strengths of the Raymond and Patsy Nasher Collection. Recognized as one of the finest collections of modern and contemporary sculpture in the world, the Nasher Collection includes masterpieces by many of the most important artists of the past 125 years such as Auguste Rodin, Henri Matisse, Constantin Brancusi, Pablo Picasso, Joan Miró, Alexander Calder, Henry Moore, Alberto Giacometti, Willem de Kooning, David Smith, Mark di Suvero, Richard Serra and Jeff Koons.

In addition to changing installations of the Collection, the Nasher Sculpture Center organizes and hosts major loan exhibitions. Drawing from public and private collections around the world, these temporary exhibitions provide context for better understanding modern and contemporary sculpture, while exploring the great variety of practices related to sculpture from the 19th century to the present including drawing, photography, installation, and architecture. Recent loan exhibitions have examined the work of historic figures such as Picasso, David Smith, Giacometti, Matisse and Calder, contemporary artists such as Jaume Plensa, Tony Cragg and Ken Price, as well as architects Renzo Piano and Norman Foster. The Nasher also commissions works from emerging and established artists for its ongoing Sightings series of installations and interventions.